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note that this step encapsulates two key problems in working with high-resolutiondata—the data were first acquired then converted, in this case by a human as opposedto computer, into clinical information. Itmay be obviated in cases of minor bleeds andknown LRTI or before bronchial artery emboli-zation in patients with known causation andlocalization of hemoptysis (Hsiao et al. More than a dozen mutations in thisregion have now been associated with either dementiaor cerebral amyloid vasculopathy in two dozen families.These mutations are thought to alter ?-amyloid metabo-lism and have been associated with chronically higherlevels of ?-amyloid, potentially a key factor leading toAD in these families. Electron micrograph of the cytoplasmic surface of the plasma membrane of A431 cells prepared by thequick-freezedeep-etch technique.
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Several genes have been implicated in Schwanncell development.